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Department of Medical Physics



Head
prof. Maria Sokół, PhD, MD

 

 

 

 

Secretariat:
telephon: +48 32 278 80 77
email: bzajac@io.gliwice.pl

 


LABORATORY OF DOSIMETRY AND QUALITY CONTROL IN RADIOTHERAPY AND RADIODIAGNOSTIC

Head
dr Andrzej Orlef, PhD
 
The mission of the Laboratory of Dosimetry and Quality Control in Radiotherapy and Radiodiagnostics is to supervise the applications of ionizing radiation in diagnostics and tumor therapy. The Laboratory supports the following organizational units of the Institute:
•          Radiotherapy Department
•          Brachytherapy Department
•          Radiodiagnostics Department
The aim of the quality control in radiotherapy and radiodiagnostics is to assure excellent patient care with advanced diagnostic and radiotherapeutic equipment. Quality assurance procedures and tests involve acceptance testing, characterization and commissioning and routine quality assurance of clinical radiotherapy systems’ use. The physicists undertake extensive efforts to improve quality assurance not only in traditional radiotherapy, but also in modern techniques, like IMRT, CyberKnife and tomotherapy. In-vivo dosimetry and dosimetric control of IMRT are routinely performed to guarantee safety of the radiotherapy procedures. Novel testing and verification procedures are being developed to ensure reliable performance as well as accurate dose delivery, especially in intra-operative radiotherapy and total body irradiation (TBI) before transplantation of bone marrow.
 
Our personnel are also involved in mammography quality control as well as supervise other radiological devices. Due to their knowledge, skills and technical competence the physicists participate in the mammography screening program coordinated by the Ministry of Health.
 
Along with the routine and scientific activities the physicists give lectures and classes for Medical Physics students of the Silesian University in Katowice.

BIOPHYSICS LABORATORY
Head
Prof. Maria Sokół, PhD, DSc
 
The Biophysics Laboratory brings together physicists and biotechnologists engaged in the studies of tumor biochemistry using NMR techniques, both in vitro and in vivo.

Our scientific interests involve high resolution 1H NMR of bio-fluids (especially of blood plasma) and high-resolution magic angle spinning (HR-MAS) NMR of soft tissues as well as applications of metabolomics in oncology.
Metabolomics, when used as a translational research tool, is expected to provide a link between the laboratory and clinic supporting its use in clinical decision making. Our aim is to establish spectral databases of metabolites and associated biochemical identities, as well as to cross-validate NMR-obtained metabolites,  correlate them with other data and integrate the results of metabolomics assessments with other ‘omics’ technology so that the entire spectrum of the malignant phenotype can be characterized.

We also perform 1H magnetic resonance in vivo spectroscopic studies of brain tumors and develop the software platform for their diagnostics support and monitoring of early metabolic effects of brain irradiation.
The animal high resolution MRI studies are focused on application of layer system releasing cytostatic and radiosensitizer directly to surgical cavity after glioma resection or to malignant tissue (in case of inoperable tumors).